Job Description
Research Associate
12-month contract
Onsite in Lexington, MA
Responsibilities
- siRNA drug candidate screening, hit identification, and lead optimization
- Cellular and molecular biology methodologies, e.g., mammalian cell culture; in vitro screening; cell-based assays; RNA extraction and RT-qPCR
- Analyze data and present the results in group meetings
- Maintain clear experimental records in laboratory notebooks; write SOPs and other technical reports as needed
- Work closely with research team members to quickly and effectively address critical questions related to the efficacy of our drugs
- Review literature and provide insights to research directions, while predominantly making hands-on contributions to the research
Qualifications
- Master’s in Cell and Molecular Biology or Pharmaceutical Sciences
- 4+ years of relevant drug discovery laboratory experience in industrial or academic environment is preferred
- Experience in cellular and molecular biology is essential (e.g., mammalian cell culture, cell-based assays, quantitative real-time PCR)
- Experience with primary human adipocytes and hepatocytes culture is preferred
- Experience with advanced in vitro model systems including organoids and other 3D culture systems is highly preferred
- Experience with RNAi and in vitro screening is preferred
- Candidate must have strong oral and written communication skills, strong work ethics and demonstrated to be an effective contributor to group projects in a team-oriented environment
- The ability to perform and interpret experiments reliably, and to advance projects aggressively towards defined goals is expected
Top Skills:
- mammalian cell culture
- cell-based assays
- quantitative real-time PCR