Job Description
Position Details:
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Job Title: Associate Research Scientist Contractor, Non-Viral Delivery (LNP)
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- Job Type: Contract
- Pay Rate: $39.04/hr on W2
- Location: 65 Hayden Avenue, Lexington, MA
- Duration: 1 year
- Work Schedule: Monday–Friday, 8:00 AM–5:00 PM
- Work Model: Onsite
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Top Skills:
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- Hands-on experience with LNP formulation and characterization
- Experience with mammalian cell culture and in vitro assays
- Strong experimental documentation, data analysis, and communication skills
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Job Description:
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Key Responsibilities:
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- Formulate and characterize nucleic acid-loaded LNPs at small to mid-scale using microfluidics, with a focus on reproducibility, scalability, quality, and consistency.
- Conduct LNP stability studies and evaluate critical formulation parameters to optimize drug product stability.
- Support ligand conjugation to LNPs, including targeted LNP development, and assist with advanced analytical characterization.
- Execute in vitro assays, including mammalian cell culture, potency, uptake, and viability assays.
- Plan, execute, document, and analyse experiments with scientific rigor and attention to detail.
- Clearly communicate experimental results through presentations, written reports, summaries, and team discussions.
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Qualifications:
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- Master’s degree with approximately 3 years of relevant experience, or PhD with 1–3 years of relevant experience, in pharmaceutical sciences, chemical engineering, bioengineering, molecular biology, biochemistry, or a related discipline.
- Hands-on experience formulating LNPs using microfluidics at small to mid-scale.
- Experience with analytical characterization techniques such as dynamic light scattering (DLS), fluorescence-based nucleic acid assays, chromatography, or related methods.
- Hands-on experience with mammalian cell culture and cell-based assays is highly desirable.
- Ability to independently follow laboratory procedures, maintain accurate records, and work within established equipment and laboratory SOPs.
- Experience with laboratory automation or high-throughput workflows is desirable.
- Experience preparing scientific reports, presentations, or publications is highly desirable.
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